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Spero Ventures

Venture capital · Burlingame, California, United States · spero.vc ↗
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How Spero Ventures invests
Stages
Seed · Series A · Series B
Sector focus
AI / ML · Fintech · Healthcare · SaaS / Enterprise · Climate Tech · Consumer · Education · Crypto / Web3
Source: Founders Bay Top 100 AI VCs (2026)
Artificial IntelligenceWellbeingSustainabilityEducation
Focus: Seed · Series A · Series B · AI

About Spero Ventures

Overview

Spero Ventures is an early-stage venture capital firm based in Burlingame, California, founded in 2018. The firm focuses on investing in purpose-led, mission-driven technology companies that aim to create a healthy, sustainable, and fulfilling future. Spero Ventures is led by experienced investors with backgrounds as startup founders and executives from notable companies like eBay and Tesla.

The firm typically leads or co-leads investment rounds ranging from $3 million to $10 million, with initial check sizes between $2 million and $4 million. Spero Ventures emphasizes a high-conviction, long

History and team

Spero's LinkedIn page lists the firm as privately held with two to ten employees and an office at 1325 Howard Ave. in Burlingame. Public directories name Sara Eshelman and Andrew Parker as general partners and Shripriya Mahesh as a general and founding partner. Startupintros also lists Rob Veres and Ha Nguyen as founding partners and Marc Tarpenning as a partner. Public sources do not say which partners lead the firm's AI deals.

AI investing

Spero's public listings show AI-branded companies in its record. ZoomInfo lists an angel or pre-seed round of $5.2 million for Alli AI. Lounge's deals desk tracks an AI seed round of $11 million for AGent Energy, dated August 2026 and marked as led. Sources do not describe the firm's AI-specific thesis beyond its general focus on purpose-led technology.

Stages and check sizes

Startupintros says the firm mainly leads seed and Series A rounds and runs a concentrated, hands-on portfolio. ZoomInfo notes that Spero keeps reserves for follow-on financing. PitchBook-style fund data from Private Equity International lists Spero Fund II as in market, with an open date of April 2024. The fund's size is not public.

Notable AI portfolio companies
  • Alli AI: AI company; ZoomInfo records a $5.2 million angel or pre-seed round. Product details and round year are not in the sources.
  • AGent Energy: $11 million seed round, August 2026, listed as led on Lounge's deals desk.
Sources

Investing activity

Spero Ventures appears in 1 AI deal tracked by the Lounge deals desk, rounds totalling $11M, and led 1 of them. The rounds are mostly Seed, with a median round size of $11M. The most recent is AGent Energy (Seed, $11M, Aug 2026).

Spero Ventures most often invests alongside MassMutual Ventures, CIV, Zero Infinity Partners and Intrepid Investment Management, and the companies it backs on Lounge are mostly in AI.

Deals

1
AI rounds and acquisitions Spero Ventures took part in, newest first.

Frequently asked questions about Spero Ventures

Does Spero Ventures invest in AI startups?

Yes, the firm has AI companies in its public record, including Alli AI. Lounge also lists an $11 million AI seed round for AGent Energy that it led.

What stages does Spero Ventures invest in?

Startupintros describes the firm as primarily leading seed and Series A rounds. Lounge tags the firm for Seed, Series A and Series B.

Who are the partners at Spero Ventures?

Public directories list Sara Eshelman and Andrew Parker as general partners and Shripriya Mahesh as a general and founding partner. Rob Veres and Ha Nguyen are listed as founding partners on Startupintros.

How large is Spero Ventures' latest fund?

Private Equity International lists Spero Fund II as in market, with an open date of April 2024. The fund size is not public.

Where is Spero Ventures based?

Spero Ventures is based in Burlingame, California, at 1325 Howard Ave.

What AI companies has Spero Ventures invested in?

Spero Ventures's AI investments include AGent Energy. The 1 round on Lounge are listed on this page with amounts, dates and co-investors.

What stage does Spero Ventures invest at?

In the rounds tracked on Lounge, Spero Ventures has invested at Seed, with a median round of $11M. Spero Ventures led 1 of those rounds.

Who does Spero Ventures co-invest with?

Spero Ventures's most frequent co-investors on Lounge are MassMutual Ventures (1 deal), CIV (1 deal), Zero Infinity Partners (1 deal) and Intrepid Investment Management (1 deal).

How can founders reach Spero Ventures?

Founders on Lounge can see Spero Ventures's contact details in AI Investor Contacts (paid plans), check for a warm introduction through members who worked with the firm under Warm Paths, and add Spero Ventures to their Investor Pipeline to track the conversation.

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