Blake Borgeson
About Blake Borgeson
Blake Borgeson studied electrical engineering at Rice University. In 2005 he co-founded BuildASign.com, an Austin online custom printing company. His own site says it was bootstrapped with no outside investment to more than $100M in revenue and then sold.
He then earned a PhD at UT Austin, applying machine learning to proteomics in the Marcotte lab. He co-founded Recursion Pharmaceuticals and was its founding CTO. Recursion uses automated cellular experiments and machine learning for drug discovery, and it went public in April 2021. He remains on Recursion's board.
In 2018 he shifted his focus from biotech to AI safety and other work on existential risk, according to the Good Forever team page. He helped lead the Machine Intelligence Research Institute (MIRI) for four years and is still a board member there. He also sits on the boards of Topos Institute and Palisade. His site says his philanthropy and investments are held through GoodForever.
Topos describes him as a key early investor and advisor for startups and nonprofits. He was on the board of the Central Texas Angel Network, starting in January 2013, per a Gritt profile that draws on LinkedIn data. CB Insights lists an angel investment dated November 2015 but does not show the company without a subscription. Crunchbase lists two personal investments in total, and Tracxn lists one. These databases are likely incomplete.
The Lounge deals desk records Theorem's $6M seed round in January 2026. Crunchbase also lists Theorem's seed round, dated January 27, 2026, among his investments. He is also listed as an investor in Leash Biosciences' $9.3M seed round in April 2024, a round Crunchbase credits to SpringTide Ventures and others. His own work and giving centre on AI safety, and he has described himself on X as keeping an eye on AI as it advances quickly.
The sources show seed-stage rounds in the US. Tracxn tags his investments as enterprise applications and high tech, and his background is in machine learning and biotech. He has not published a check size, a fund size or a stated investment thesis that we could find. Founders should not assume a typical cheque size or sector preference beyond these examples.
- Theorem: seed round of $6M, January 2026
- Leash Biosciences (Leash Bio): seed round of about $9.3M, April 2024, alongside SpringTide and other investors
Investing activity
Blake Borgeson appears in 1 AI deal tracked by the Lounge deals desk. The rounds are mostly Seed, with a median round size of $6M. The most recent is Theorem (Seed, $6M, Jan 2026).
Blake Borgeson most often invests alongside Khosla Ventures, Safe AI Fund, E14 Fund and Y Combinator, and the companies they back on Lounge are mostly in AI.
Deals
Frequently asked questions about Blake Borgeson
Who is Blake Borgeson?
He is an entrepreneur, computational biologist and angel investor. He co-founded BuildASign.com and Recursion Pharmaceuticals, where he was founding CTO and is still a board member. He is also on the boards of MIRI, Topos Institute and Palisade.
Has Blake Borgeson invested in AI startups?
Yes. He took part in Theorem's $6M seed round in January 2026. Crunchbase also lists him in Leash Bio's seed round in April 2024.
What is Blake Borgeson's check size?
He has not published one, so we do not list a figure. Ask him directly, or through a mutual contact, before you assume a range.
What stage does Blake Borgeson invest in?
The public records show seed rounds, namely Theorem in 2026 and Leash Bio in 2024. They do not describe a formal stage policy.
How can founders contact Blake Borgeson?
He is on LinkedIn and on X as @blakeweb. His personal site is blakeb.org. A warm introduction from someone in AI safety or biotech is likely to help, though he has not said how he prefers to be approached.
Does Blake Borgeson care about AI safety?
Yes. Good Forever describes him as a donor and strategist in AI safety. He serves on MIRI's board and on the boards of Topos Institute and Palisade.
Is Blake Borgeson an angel investor?
Yes. Blake Borgeson invests personally as an angel.
What AI companies has Blake Borgeson invested in?
Blake Borgeson's AI investments include Theorem. The 1 round on Lounge are listed on this page with amounts, dates and co-investors.
What stage does Blake Borgeson invest at?
In the rounds tracked on Lounge, Blake Borgeson has invested at Seed, with a median round of $6M.
Who does Blake Borgeson co-invest with?
Blake Borgeson's most frequent co-investors on Lounge are Khosla Ventures (1 deal), Safe AI Fund (1 deal), E14 Fund (1 deal), Y Combinator (1 deal) and Pioneer Fund (1 deal).